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Definition of terms from gemstone information manual:   

Synthetic: Refers to a man-made material with a natural counterpart. The synthetic crystal replicates the chemical and physical properties of the natural crystal with little or no variation. Synthetic gemstones are also known as lab-created stones.


Man-made: Used for a manufactured product fabricated in such materials as glass, ceramic or plastic designed to imitate or resemble the appearance, but not duplicates the characteristic properties of a natural gemstone. Also can be listed as imitation.